Did your Windows 10 PC recently update, leaving your Pastel Xpress 11 or 12 no longer functional?
Getting the error
-2147221503 The Application is not valid. Please specify the correct Application Path. Registration Checking Cannot Continue.
Right-click the Xpress icon on the desktop, click Properties then go to the Compatibility tab and click the checkbox for Run this program as an administrator and you should be good to go.
If this doesn’t work you can try, under the same Compatibility tab, “Run this program in compatibility mode for:” check the checkbox and then select Windows 7.